High incidence of chromosome abnormalities in IgG3 myeloma.
Cancer Genet Cytogenet
; 11(4): 381-7, 1984 Apr.
Article
en En
| MEDLINE
| ID: mdl-6704939
ABSTRACT
Chromosomes were studied in 33 untreated myeloma patients, and results were correlated with the class of Ig secreted by the myeloma cells. A high incidence of clonal karyotypic anomalies seemed to be present in IgG3 myeloma patients, in whom the disease was advanced at diagnosis and rapidly progressing. Among the chromosome anomalies, the t(11;14)(q14;q32) was particularly prominent, and this chromosome anomaly, in analogy with the Ph1 chromosome, may characterize a family of lymphoproliferative disorders.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Aberraciones Cromosómicas
/
Mieloma Múltiple
Tipo de estudio:
Incidence_studies
/
Risk_factors_studies
Límite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Cancer Genet Cytogenet
Año:
1984
Tipo del documento:
Article