Differential expression of intermediate-filament proteins in murine sarcoma 180 ascites or solid tumor.
Cancer Res
; 44(6): 2590-4, 1984 Jun.
Article
en En
| MEDLINE
| ID: mdl-6722795
ABSTRACT
The intermediate-filament proteins in Sarcoma 180 ascites cells and solid tumors generated by s.c. injection of ascites cells in NMRI or nude mice were analyzed by one- and two-dimensional gel electrophoresis and identified by immunological methods. The ascites form of Sarcoma 180 coexpresses keratin and vimentin, whereas the solid tumor ceases to synthesize keratins but continues to express vimentin. These reversible changes in the expression of intermediate-filament proteins may be due to a change in the differentiation program induced by environmental conditions like growth with or without cell contact.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Sarcoma 180
/
Sarcoma de Yoshida
/
Proteínas de Filamentos Intermediarios
Límite:
Animals
Idioma:
En
Revista:
Cancer Res
Año:
1984
Tipo del documento:
Article