Demonstration of hypnozoites in sporozoite-transmitted Plasmodium vivax infection.
Am J Trop Med Hyg
; 31(6): 1291-3, 1982 Nov.
Article
en En
| MEDLINE
| ID: mdl-6816080
ABSTRACT
Hypnozoites of two strains of the human relapsing malaria parasite, Plasmodium vivax, have been detected among maturing 7- and 10-day pre-erythrocytic schizonts in liver biopsies of chimpanzees infected by intravenous inoculation of sporozoites obtained from dissected salivary glands of heavily infected anopheline mosquitoes. As in the simian relapsing species, P. cynomolgi, the hypnozoites of P. vivax at 7 and 10 days are uninucleate forms of approximately 4-5 micrometers diameter, lying within the cytoplasm of individual hepatocytes. Their presence in this relapsing human species is added support for the hypnozoite theory of malarial relapse.
Buscar en Google
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Malaria
Tipo de estudio:
Etiology_studies
Límite:
Animals
Idioma:
En
Revista:
Am J Trop Med Hyg
Año:
1982
Tipo del documento:
Article