Development of a gas chromatography mass spectrometry assay for the two eosinophil chemotactic factors of anaphylaxis.
Biomed Mass Spectrom
; 10(3): 120-5, 1983 Mar.
Article
en En
| MEDLINE
| ID: mdl-6850065
ABSTRACT
Gas chromatography mass spectrometry has been used for over a decade for the determination of the amino acid sequences of fragment peptides derived from larger parent molecules. The majority of these fragments have from four to seven residues and several different methods of derivatization have been devised. Few reports have been published in which similar techniques have been used for the quantification of such peptides, but there is a growing list of small peptides which have been shown to have biological activity in their own right. This report is concerned with the development of a gas chromatographic mass spectrometric assay for the two eosinophil chemotactic peptides, Val-Gly-Ser-Glu and Ala-Gly-Ser-Glu, which appear to have a role to play in the course of the inflammatory process in skin disorders.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Factores Quimiotácticos
/
Factores Quimiotácticos Eosinófilos
/
Anafilaxia
Límite:
Humans
Idioma:
En
Revista:
Biomed Mass Spectrom
Año:
1983
Tipo del documento:
Article