Factor IX thrombogenicity: in vivo effects on coagulation activation and a case report of disseminated intravascular coagulation.
Thromb Haemost
; 48(1): 76-7, 1982 Aug 24.
Article
en En
| MEDLINE
| ID: mdl-7135346
ABSTRACT
An episode of defibrination with bleeding following high dose Edinburgh Factor IX (D.E.F.IX) replacement in a patient with haemophilia B undergoing knee joint replacement is reported. We have also monitored plasma fibrinopeptide A levels in patients with haemophilia B following ten standard doses of D.E.F.IX (15-20 u/kg) and have been unable to document any change. Activation of the coagulation system, as previously noted, appears to be related to the use of Factor IX concentrates in high doses.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Coagulación Sanguínea
/
Factor IX
/
Coagulación Intravascular Diseminada
Límite:
Adult
/
Humans
/
Male
Idioma:
En
Revista:
Thromb Haemost
Año:
1982
Tipo del documento:
Article