Members of a family of Drosophila putative odorant-binding proteins are expressed in different subsets of olfactory hairs.
Neuron
; 12(1): 35-49, 1994 Jan.
Article
en En
| MEDLINE
| ID: mdl-7545907
ABSTRACT
A polymerase chain reaction-based method was used to generate a Drosophila melanogaster antennal cDNA library from which head cDNAs were subtracted. We identified five cDNAs that code for antennal proteins containing six cysteines in a conserved pattern shared with known moth antennal proteins, including pheromone-binding proteins. Another cDNA codes for a protein related to vertebrate brain proteins that bind hydrophobic ligands. In all, we describe seven antennal proteins which contain potential signal peptides, suggesting that, like pheromone-binding proteins, they may be secreted in the lumen of olfactory hairs. The expression patterns of these putative odorant-binding proteins define at least four different subsets of olfactory hairs and suggest that the Drosophila olfactory apparatus is functionally segregated.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Receptores Odorantes
/
Drosophila melanogaster
Límite:
Animals
Idioma:
En
Revista:
Neuron
Asunto de la revista:
NEUROLOGIA
Año:
1994
Tipo del documento:
Article