The importance of the quality of water in Limulus Amebocyte Lysate tests.
PDA J Pharm Sci Technol
; 49(3): 119-21, 1995.
Article
en En
| MEDLINE
| ID: mdl-7613989
ABSTRACT
Commercial pharmaceutical waters were evaluated regarding their interference in the chromogenic Limulus Amebocyte Lysate (LAL) test. Two of the four tested waters strongly inhibited the U.S. Reference Standard Endotoxin, while a Control Standard Endotoxin was less affected. The inhibitory effect could be mimiced by adding trace amounts of certain metal ions to a non-interfering water. In conclusion, the water used in the LAL test must be chosen with great care.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Endotoxinas
/
Escherichia coli
/
Agua Dulce
/
Prueba de Limulus
Idioma:
En
Revista:
PDA J Pharm Sci Technol
Asunto de la revista:
FARMACIA
/
FARMACOLOGIA
Año:
1995
Tipo del documento:
Article
País de afiliación:
Suecia