Formoguanamine-induced inhibition of deprivation myopia in chick is accompanied by choroidal thinning while retinal function is retained.
Vision Res
; 35(14): 2075-88, 1995 Jul.
Article
en En
| MEDLINE
| ID: mdl-7660611
ABSTRACT
Twenty hatchling chickens were injected intravitreally every 4 days from day 2 to day 16 with dimethyl sulphoxide (DS) in one eye and DS or formoguanamine dissolved in DS (FG.DS) with or without occlusion in the other (FG.DS.MD, DS.MD, FG.DS). At day 16, the FG.DS.MD eyes failed to show the high refractive myopia and showed less axial elongation than that developed by the DS.MD eyes. Electroretinograms indicated that at the dosage used, FG.DS does not eliminate phototransduction. Light microscopy showed choroidal and retinal thinning in DS.MD and FG.DS.MD eyes but less than in FG.DS eyes, suggesting that change in choroidal thickness is unlikely to be the primary cause of form deprivation myopia.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Retina
/
Triazinas
/
Coroides
/
Miopía
Tipo de estudio:
Etiology_studies
Límite:
Animals
Idioma:
En
Revista:
Vision Res
Año:
1995
Tipo del documento:
Article
País de afiliación:
Australia