Molluscicidal saponins from a Zimbabwean strain of Phytolacca dodecandra.
Phytochemistry
; 36(3): 753-9, 1994 Jun.
Article
en En
| MEDLINE
| ID: mdl-7765003
ABSTRACT
Three new monodesmosidic saponins, all glycosides of 2 beta-hydroxyoleanolic acid, were isolated from an aqueous extract of a Zimbabwean strain of Phytolacca dodecandra. Their structures were, mainly by spectroscopic methods (LSIMS, 1H NMR, COSY, NOESY, TOCSY, J-resolved 1H NMR, 13C NMR, HETCOR), established as 3-O-[2',4'-di-O-(beta-D-glucopyranosyl)-beta-D-glucopyranosyl]2 beta-hydroxyoleanolic acid, 3-O-[O-alpha-L-rhamnopyranosyl-(1-->2)-O-[beta-D-galactopyranosyl- (1-->3)]-beta-D-glucopyranosyl]2 beta-hydroxyoleanolic acid and 3-O-[3'-O-(beta-D-galactopyranosyl)-beta-D-glucopyranosyl]2 beta-hydroxyoleanolic acid. Two of the saponins were submitted to a preliminary screening for molluscicidal activity against the schistosomiasis transmitting snail Biomphalaria glabrata and showed, respectively, strong and weak activity. In addition, four saponins previously reported from other strains of Phytolacca dodecandra were identified.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Plantas
/
Saponinas
/
Moluscocidas
Límite:
Animals
País/Región como asunto:
Africa
Idioma:
En
Revista:
Phytochemistry
Año:
1994
Tipo del documento:
Article