Characterization of Mycobacterium tuberculosis strains from Vietnamese patients by Southern blot hybridization.
J Clin Microbiol
; 31(6): 1615-8, 1993 Jun.
Article
en En
| MEDLINE
| ID: mdl-8100244
ABSTRACT
A total of 41 Mycobacterium tuberculosis strains from patients of Vietnamese origin were analyzed by Southern blot hybridization with two different probes, IS6110 (Otal, I., et al., J. Clin. Microbiol. 291252-1254, 1991; Ross, B. C., et al., J. Clin. Microbiol. 30942-946, 1992; Thierry, D., et al., J. Clin. Microbiol. 282668-2673, 1990; van Soolingen, D., et al., J. Clin. Microbiol. 292578-2586, 1991) and pTBN12 (Ross, B. C., et al., J. Clin. Microbiol. 30942-946, 1992). The restriction fragment patterns of nine of these strains were virtually identical when the pTBN12 probe was used; five strains had a single copy of IS6110, and four strains failed to hybridize with the IS6110 probe. This relatively high frequency of strains with no or one copy of IS6110 suggests that the usefulness of IS6110 for epidemiological study may be limited in certain populations.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Mycobacterium tuberculosis
Tipo de estudio:
Diagnostic_studies
/
Evaluation_studies
Límite:
Female
/
Humans
/
Male
País/Región como asunto:
Asia
/
Oceania
Idioma:
En
Revista:
J Clin Microbiol
Año:
1993
Tipo del documento:
Article
País de afiliación:
Australia