The utility of verbal autopsies for identifying HIV-1-related deaths in Haitian children.
AIDS
; 7(9): 1255-9, 1993 Sep.
Article
en En
| MEDLINE
| ID: mdl-8216984
ABSTRACT
OBJECTIVE:
To determine whether deaths among Haitian infants born to HIV-1-seronegative women could be distinguished from deaths among children born to HIV-1-seropositive women using the verbal autopsy technique.METHODS:
Mothers of 315 Haitian children who died were interviewed about events leading to the child's death. Three physicians independently reviewed interview data and determined the probable cause of death without knowledge of maternal HIV-1 status or hospital records. The underlying causes of death assigned to the infants were analyzed to determine whether maternal HIV status could be predicted.RESULTS:
There was good agreement among the physicians (kappa = 0.62) and 90% agreement between hospital records and the verbal autopsy diagnosis. Compared with children born to HIV-1-seronegative women, deaths in children born to HIV-1-seropositive mothers were more likely to be ascribed to a presumptive diagnosis of AIDS (37 versus 21%; P = 0.01). The sensitivity and specificity of verbal autopsies for identifying deaths associated with maternal HIV-1 infection ranged from 37 to 59% and from 69 to 79%, respectively, depending on the classification system used. The predictive positive value of a death believed to be consistent with pediatric HIV-1 infection was 26-30% and the predictive negative value was 85-90%.CONCLUSION:
Verbal autopsies may be useful for distinguishing certain causes of death, but have limited utility for distinguishing deaths associated with maternal HIV-1 infection from deaths among children born to HIV-1-seronegative women.Palabras clave
Age Factors; Americas; Caribbean; Causes Of Death; Child; Child Mortality; Congenital Abnormalities; Data Collection; Demographic Factors; Developing Countries; Diseases; Family And Household; Family Characteristics; Family Relationships; Haiti; Hiv Infections; Interviews; Latin America; Measurement; Mortality; Mothers; Neonatal Diseases And Abnormalities; North America; Parents; Population; Population Characteristics; Population Dynamics; Research Methodology; Validity; Viral Diseases; Youth
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Síndrome de Inmunodeficiencia Adquirida
Tipo de estudio:
Diagnostic_studies
/
Prognostic_studies
Límite:
Child, preschool
/
Female
/
Humans
/
Infant
/
Pregnancy
País/Región como asunto:
Caribe
/
Haiti
Idioma:
En
Revista:
AIDS
Asunto de la revista:
SINDROME DA IMUNODEFICIENCIA ADQUIRIDA (AIDS)
Año:
1993
Tipo del documento:
Article