Identification of Mycobacterium tuberculosis DNA in five different types of cutaneous lesions by the polymerase chain reaction.
Arch Dermatol
; 129(12): 1594-8, 1993 Dec.
Article
en En
| MEDLINE
| ID: mdl-8250581
ABSTRACT
BACKGROUND AND DESIGN:
A spectrum of skin lesions are believed to be secondary to the presence of Mycobacterium tuberculosis. Demonstration of M tuberculosis directly or in culture in some of these eruptions can be difficult. We used the polymerase chain reaction and a primer/probe set specifically for M tuberculosis complex DNA to evaluate five types of skin lesions clinically considered to represent infection by, or reaction to, M tuberculosis. OBSERVATIONS Mycobacterium tuberculosis DNA was demonstrated in paraffin-embedded sections of these five cases, representing a variety of clinical and histologic patterns. In two cases, M tuberculosis could not be demonstrated by routine cultural methods.CONCLUSION:
DNA diagnostic methods such as the polymerase chain reaction can be used to rapidly identify cutaneous lesions produced by M tuberculosis.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Tuberculosis Cutánea
/
ADN Bacteriano
/
Mycobacterium tuberculosis
Tipo de estudio:
Diagnostic_studies
/
Prognostic_studies
Límite:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Arch Dermatol
Año:
1993
Tipo del documento:
Article
País de afiliación:
Macao