(+)-10 alpha-Hydroxy-4-muurolen-3-one, a new inhibitor of leukotriene biosynthesis from a Favolaschia species. Comparison with other sesquiterpenes.
Z Naturforsch C J Biosci
; 51(7-8): 487-91, 1996.
Article
en En
| MEDLINE
| ID: mdl-8810091
ABSTRACT
A new inhibitor of leukotriene biosynthesis, (+)-10 alpha-hydroxy-4-muurolen-3-one (1), was isolated from fermentations of Favolaschia sp. 87129. Its structure was established by spectroscopic methods. The compound exhibited no antifungal or antibacterial activities. The effects of 1 on leukotriene biosynthesis were compared with (+)-T-cadinol, (-)-3-oxo-T-cadinol, and (+)-3 alpha-hydroxy-T-cadinol, three related sesquiterpenes.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Polyporaceae
/
Sesquiterpenos
/
Leucotrienos
/
Leucocitos
/
Antineoplásicos Fitogénicos
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Z Naturforsch C J Biosci
Año:
1996
Tipo del documento:
Article