Association of ABO blood type with mortality in hospitalized patients with COVID-19 / Asociación de los grupos sanguíneos ABO con la mortalidad en pacientes hospitalizados por COVID-19
Vázquez-Medina, Martín Uriel; Cerda-Reyes, Eira; Barrón-Campos, Arcelia Carolina; Almeyda-Farfán, José Antonio; Ocharan-Hernández, María Esther; Vargas-De-León, Cruz.
Horiz. sanitario (en linea)
; 21(1): 17-24, Jan.-Apr. 2022. tab, graf
Artigo
em Inglês
|
LILACS-Express
| ID: biblio-1448386
Abstract
Objective:
To explore the relation between ABO blood group system and in-hospital mortality in Mexican patients admitted with COVID-19. Materials andmethods:
We performed a retrospective study with 2,369 hospitalized patients with confirmed SARS-CoV-2 infection in a tertiary referral hospital, admitted between March 27 and December 10, 2020. Data were obtained from electronic health records. Adjusted and unadjusted Cox Proportional-Hazard models were performed to test the association of ABO blood groups with mortality of COVID-19 patients. The variables considered for adjustment of the models were age, sex, and main comorbidities.Results:
Out of all studied patients, group O was the most frequent blood type with 1999 patients (84.3%), followed by group A (11.3%), B (3.5%) and AB (0.72%). Blood group A was associated with a lower hazard of death among COVID-19 patients compared with group O (adjusted HR = 0.72, 95% IC 0.55-0.95, P = 0.02. Groups B, AB and Positive Rh were not significantly associated with the outcome.Conclusions:
We found evidence of a statistically significant association between ABO blood type and COVID-19 in-hospital death. Patients with blood group A may be less likely to die during hospitalization compared with group O.
Biblioteca responsável:
MX1.1
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