Risk factors associated with actinic prurigo: a case control study
An. bras. dermatol
; An. bras. dermatol;92(6): 774-778, Nov.-Dec. 2017. tab
Article
em En
| LILACS
| ID: biblio-887115
Biblioteca responsável:
BR1.1
ABSTRACT
Abstract Background:
Actinic prurigo (AP) is an idiopathic photodermatosis. Although its initial manifestations can appear in 6 to 8-year-old children, cases are diagnosed later, between the second and fourth decades of life, when the injuries are exacerbated.Objective:
To identify risk factors associated with clinical manifestations of AP such as skin and mucosal lesions.Methods:
Thirty patients with AP and 60 controls were included in the study, the dependent variable was the presence of skin or labial mucosal lesions, the independent variables were age, sex, solar exposure, living with pets or farm animals, exposure to wood smoke, smoking habit, years smoking, and hours spent per day and per week in contact with people who smoke.Results:
Of the 30 diagnosed AP patients, 66.7% were female. Patients age ranged from 7 to 71 years and the mean age was 35.77 ± 14.55 years. We found significant differences with the age and cohabitation with farm animals. Those who lived with farm animals presented 14.31 times higher probability of developing AP (95% CI 3-78.06). Studylimitations:
This is a case-control study; therefore, a causal relationship cannot be proven, and these results cannot be generalized to every population.Conclusions:
The identification of factors related to the development of AP increases our knowledge of its physiopathology. Moreover, identifying antigens that possibly trigger the allergic reaction will have preventive and therapeutic applications in populations at risk of AP.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
LILACS
Assunto principal:
Transtornos de Fotossensibilidade
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Dermatopatias Genéticas
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Exposição Ambiental
Tipo de estudo:
Etiology_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Animals
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Female
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Humans
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Male
Idioma:
En
Revista:
An. bras. dermatol
Assunto da revista:
DERMATOLOGIA
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
México