Carga viral en liquido cefalorraquideo de pacientes hemofílicos HIV-1 positivos bajo tratamiento con HAART / Cerebrospinal fluid viral load in HIV-1 positive hemophilic patients treated with HAART
Medicina (B.Aires)
; 61(6): 821-4, 2001. tab
Article
em Es
| LILACS
| ID: lil-300784
Biblioteca responsável:
BR1.1
RESUMO
As HIV seropositive patients with undetectable CSF viral load have a lower likelihood of developing neurologic disease, the determination of CSF viral load levels may be useful to evaluate the efficacy of HAART. We compared plasma viral load levels with HIV-1 RNA CSF levels in 18 hemophilic patients without neurocognitive involvement under HAART. We detected a significant correlation between plasma viral load levels and CSF viral load levels. Fourteen patients with undetectable plasma viral load had undetectable RNA HIV-1 CSF levels as well. Four patients with detectable plasma viral load had detectable HIV-RNA in CSF, but the latter were significantly lower. Viral load is usually lower in non-blood fluids and HAART decreases the viral load in CSF as well as in blood.
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Coleções:
01-internacional
Base de dados:
LILACS
Assunto principal:
RNA Viral
/
Infecções por HIV
/
HIV-1
/
Carga Viral
/
Terapia Antirretroviral de Alta Atividade
/
Hemofilia A
Limite:
Humans
Idioma:
Es
Revista:
Medicina (B.Aires)
Assunto da revista:
MEDICINA
Ano de publicação:
2001
Tipo de documento:
Article
País de afiliação:
Argentina