Delirium in hospitalized elderly patients and post-discharge mortality
Clinics
; 65(3): 251-255, 2010. ilus, tab
Article
em En
| LILACS
| ID: lil-544016
Biblioteca responsável:
BR1.1
ABSTRACT
OBJECTIVE:
To determine the impact of delirium on post-discharge mortality in hospitalized older patients.INTRODUCTION:
Delirium is frequent in hospitalized older patients and correlates with high hospital mortality. There are only a few studies about its impact on post-discharge mortality.METHODS:
This is a prospective study of patients over 60 years old who were hospitalized in the Geriatric Unit at Hospital das Clínicas of São Paulo between May 2006 and March 2007. Upon admission, demographics, comorbidities, number of drugs taken, and serum albumin concentration were evaluated for each patient. Delirium was diagnosed according to the DSM-IV criteria. Patients were divided into group A (with delirium) and group B (without delirium). One year after discharge, the patients or their caregivers were contacted to assess days of survival.RESULTS:
The sample included 199 patients, 66 (33 percent) of whom developed delirium (Group A). After one year, 33 (50 percent) group A patients had died, and 45 (33.8 percent) group B patients had died (p = 0.03). There was a significant statistical difference in average age (p = 0.001) and immobility (p <0.001) between groups A and B. There were no statistically significant differences between groups A and B in number of drugs taken greater than four (p = 0.62), sex (p = 0.54) and number of diagnoses greater than four (p = 0.21). According to a multivariate analysis, delirium was not an independent predictor of post-discharge mortality. The predictors of post-discharge mortality were age > 80 years (p = 0.029), albumin concentration < 3.5 g/dl (p = 0.001) and immobility (p = 0.007).CONCLUSION:
Delirium is associated with higher post-discharge mortality as a dependent predictor.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
LILACS
Assunto principal:
Alta do Paciente
/
Delírio
/
Hospitalização
Tipo de estudo:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Aged
/
Aged80
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Clinics
Assunto da revista:
MEDICINA
Ano de publicação:
2010
Tipo de documento:
Article
País de afiliação:
Brasil