[Detection of Epstein-Barr virus in Malt type gastric malignant lymphoma using in situ hybridization]. / Recherche du virus d'Epstein Barr dans les lymphomes malins de type Malt gastriques par hybridation in situ.

The aim of our study was to look for Epstein Barr virus (EBV) genome by in situ hybridization in 23 MALT gastric lymphomas. 15 cases were of low grade, and 8 were of high grade malignancy. We obtained a positive result in 3 cases (13%) of low grade lymphomas. EBV was present in few centrocyte-like and centroblastic cells. Literature review shows an EBV infection rate varying between 8 and 12% with variables results which don't allow strong and reliable conclusion. An etiopathogenic role for EBV in Malt gastric lymphoma remain yet hypothetic.