Epidemiology of Haemophilus influenzae invasive disease in hospitalised Kelantanese children, 1985-1994.
Singapore Med J
; 40(2): 96-100, 1999 Feb.
Article
em En
| MEDLINE
| ID: mdl-10414167
ABSTRACT
AIM:
Data is lacking with regard to the epidemiology of invasive haemophilus influenzae (HI) disease in Malaysia. This study was carried out to document the epidemiology of invasive HI disease in hospitalised Kelantanese children.METHODS:
We conducted a retrospective study of 65 children who had invasive HI disease from June 1985 to December 1994. Data regarding age, sex, duration of illness, weight, diagnosis, complications, duration of hospitalisation, outcome, full blood count and sensitivity pattern of HI to various antibiotics were reviewed.RESULTS:
The age distribution varied from one day to 72 months with a mean of 13 months. Peak incidence occurred in the 7-12 months age group. Majority (89.1%) was below two years of age. The relative frequencies of the 75 clinical entities documented were as follows meningitis 64%, pneumonia 29.3%, septicaemia 5.4%, and abscess 1.3%. In addition, 13.5% of cases had meningitis associated with pneumonia. Serotype b accounted for all strains in cases where serotyping was done. Anaemia (Hb < 10 g%) was seen in 71.4% of cases. Long term complications were noted in 41.5% of cases of meningitis. Case fatality rate was 12.3%. The percentage of HI strains sensitive to penicillin, ampicillin, chloramphenicol and co-trimoxazole were 83.7%, 87.7%, 98.2% and 89.7%, respectively.CONCLUSION:
The data suggest that invasive HI disease causes considerable morbidity and mortality in Kelantanese children.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Haemophilus influenzae
/
Infecções por Haemophilus
Tipo de estudo:
Observational_studies
/
Risk_factors_studies
/
Screening_studies
Limite:
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
/
Newborn
País/Região como assunto:
Asia
Idioma:
En
Revista:
Singapore Med J
Ano de publicação:
1999
Tipo de documento:
Article
País de afiliação:
Malásia