Use of diclofenac in children with asthma.
Anaesthesia
; 55(4): 334-7, 2000 Apr.
Article
em En
| MEDLINE
| ID: mdl-10781118
ABSTRACT
This study investigated the effect of diclofenac on the lung function of 70 children aged 6-15 years with a diagnosis of asthma, recruited from a hospital respiratory clinic. Peak flow and a forced expiratory flow-volume loop were measured and the patients were then given 1-1.5 mg.kg-1 effervescent diclofenac orally. Spirometry was repeated at 10, 20 and 30 min, a 15% decrease in results being considered a significant reduction in lung function. No patient demonstrated a consistent reduction in lung function of > 15% during the study and there were no reports of wheezing or increased bronchodilator use after completion of the spirometry. In conclusion, we studied a group of genuine asthmatics and found no clinically significant incidence of bronchospasm with the use of a single therapeutic dose of diclofenac.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Asma
/
Mecânica Respiratória
/
Anti-Inflamatórios não Esteroides
/
Diclofenaco
Limite:
Adolescent
/
Child
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Anaesthesia
Ano de publicação:
2000
Tipo de documento:
Article
País de afiliação:
Reino Unido