Lack of association of the Ala45Thr variant in the BETA2/NEUROD1 with type 1 diabetes in Japanese.
Diabetes Res Clin Pract
; 49(1): 61-3, 2000 Jul.
Article
em En
| MEDLINE
| ID: mdl-10808064
ABSTRACT
To evaluate the role of the Ala45Thr variant of BETA2/NEUROD1 in the development of type 1 or type 2 diabetes, we studied a Japanese population consisting of 383 control subjects, 234 type 1 diabetes patients and 160 type 2 diabetes patients. Both genotypewise and allelewise, there was no significant association of the variant with type 1 diabetes or type 2 diabetes in Japanese. Also, there were no significant differences in clinical characteristics with and without the variant. Our present results do not support a recent report which described an association of the Ala45Thr variant with type 1 diabetes in Japanese.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Transativadores
/
Diabetes Mellitus Tipo 1
/
Diabetes Mellitus Tipo 2
/
Proteínas de Ligação a DNA
Tipo de estudo:
Risk_factors_studies
Limite:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
País/Região como assunto:
Asia
Idioma:
En
Revista:
Diabetes Res Clin Pract
Assunto da revista:
ENDOCRINOLOGIA
Ano de publicação:
2000
Tipo de documento:
Article
País de afiliação:
Japão