The role of fluoroquinolones in respiratory tract infections: community acquired pneumonia.
Int J Antimicrob Agents
; 16(3): 281-5, 2000 Nov.
Article
em En
| MEDLINE
| ID: mdl-11091048
ABSTRACT
Newer fluoroquinolones may play an important role in the management of community acquired pneumonia. They retain activity similar to older fluoroquinolones against Gram-negative bacteria and are significantly more active against Gram-positive bacteria, especially pneumococci. They are also active against bacteria causing atypical pneumonia, penicillin-sensitive and -resistant and macrolide-sensitive and -resistant pneumococci and against beta-lactamase producing and non-producing Haemophilus influenzae. They have similar or slightly lower activity than ciprofloxacin against other Gram-negative organisms. They have rapid bactericidal activity and attain good lung tissue levels. Clinical studies show results similar or better than older treatments. Their impact on ecology and resistance remains to be elucidated but data on side effects and toxicity must be carefully evaluated.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Infecções Respiratórias
/
Infecções Comunitárias Adquiridas
/
Pneumonia Bacteriana
/
Anti-Infecciosos
Limite:
Humans
/
Middle aged
Idioma:
En
Revista:
Int J Antimicrob Agents
Ano de publicação:
2000
Tipo de documento:
Article
País de afiliação:
Espanha