Membrane fluidity correlates with liver cancer cell proliferation and infiltration potential.

Funaki, N O; Tanaka, J; Kohmoto, M; Sugiyama, T; Ohshio, G; Nonaka, A; Yotsumoto, F; Takeda, Y; Imamura, M

Funaki, N O; Tanaka, J; Kohmoto, M; Sugiyama, T; Ohshio, G; Nonaka, A; Yotsumoto, F; Takeda, Y; Imamura, M.

Afiliação

Funaki NO; Department of Surgery, Shiga Medical Center for Adults, Moriyama City, Japan.

Oncol Rep ; 8(3): 527-32, 2001.

Article em En | MEDLINE | ID: mdl-11295074

RESUMO

We developed a method to measure membrane fluidity of living cancer cells in two- and three-dimensional cultures, and found that there was a close relationship between the membrane fluidity of cancer cells and their proliferative and infiltrative ability. Membrane fluidity is thus a promising indicator of the probability of cancer recurrence.

Assuntos

Carcinoma Hepatocelular/patologia; Membrana Celular/fisiologia; Neoplasias Hepáticas/patologia; Fluidez de Membrana; Bromodesoxiuridina; Divisão Celular; Polarização de Fluorescência; Humanos; Microscopia de Contraste de Fase; Modelos Biológicos; Células Tumorais Cultivadas

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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Membrana Celular / Carcinoma Hepatocelular / Neoplasias Hepáticas / Fluidez de Membrana Limite: Humans Idioma: En Revista: Oncol Rep Assunto da revista: NEOPLASIAS Ano de publicação: 2001 Tipo de documento: Article País de afiliação: Japão

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