Case of lipoblastoma with two derivative chromosomes 8 containing homogeneously staining-like regions and a review of the literature: lipoblastoma and chromosome 8.

ABSTRACT

We report a case of a lipoblastoma in a 10-month-old girl in which the cytogenetic aberration showed a homogeneously staining-like region (hsr) within two derivative chromosomes 8. There was a loss of one normal copy of chromosome 8 and gain of two identical derivative chromosomes 8 with the karyotype designation 47,XX,psu idic(8)(pter-->q12 approximately 13hsrq12 approximately 13-->pter),+psu idic (8)(pter-->q12 approximately 13hsrq12 approximately 13-->pter). This is the first report of a chromosomal aberration of this type seen in lipoblastoma.