Identification of post-translationally modified proteins in proteome studies.
Electrophoresis
; 22(9): 1669-76, 2001 May.
Article
em En
| MEDLINE
| ID: mdl-11425222
ABSTRACT
Proteome studies are powerful tools to solve many different problems in metabolism, signal transduction, drug discovery, and other areas of interest in life sciences. Up to now, high-sensitive methods for protein identification after two-dimensional gel electrophoresis using mass spectrometry are available. However, the identification of post-translational modifications after two-dimensional gel electrophoresis is still an unsolved problem. In this paper, we want to give several examples for the successful identification of post-translational modifications and point mutations.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Proteoma
Tipo de estudo:
Diagnostic_studies
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Electrophoresis
Ano de publicação:
2001
Tipo de documento:
Article
País de afiliação:
Alemanha