Prevalence and mortality of the Brugada-type electrocardiogram in one city in Japan.
J Am Coll Cardiol
; 38(3): 771-4, 2001 Sep.
Article
em En
| MEDLINE
| ID: mdl-11527631
ABSTRACT
OBJECTIVES:
We sought to study the prevalence and mortality of subjects exhibiting the Brugada-type electrocardiogram (ECG) in a community-based population in Japan.BACKGROUND:
The Brugada syndrome has been associated with sudden death in subjects without structural heart disease. Hospital-based studies showed 11% to 38% annual fatal arrhythmic events in patients with the Brugada syndrome.METHODS:
Prevalence and mortality of the Brugada-type ECG were studied in subjects who had ECGs during a health examination in Moriguchi, Osaka, Japan. Information about death and relocation from Moriguchi city was obtained prospectively.RESULTS:
The Brugada-type ECG was found in 98 of 13,929 study subjects (0.70%, 95% confidence interval [CI] 0.57% to 0.86%). The typical coved-type with an rsR' pattern in V(1) lead ("typical" Brugada-type) was found in 0.12% of subjects (95% CI 0.07% to 0.20%). The prevalence for male subjects with the Brugada-type ECG (81%) was significantly higher than it was for those without (26%, p < 0.0001). In male subjects, the Brugada-type ECG was found in 2.14% (95% CI 1.70% to 2.66%), and the "typical" Brugada-type was found in 0.38% (95% CI 0.21% to 0.64%). After 2.6 +/- 0.3 years of follow-up, there was 1 death (1.0%, 95% CI 0.03% to 5.6%) of a subject with the Brugada-type ECG, whereas there were 139 deaths (1.0%, 95% CI 0.85% to 1.2%) of those without the Brugada-type ECG (p = 0.9943, log-rank test).CONCLUSIONS:
A substantial number of the Brugada-type ECG were observed in subjects in a community-based population in Japan, especially in men. The total mortality of subjects with the Brugada-type ECG did not differ from the mortality of those without the Brugada-type ECG in a community-based population.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fibrilação Ventricular
/
Bloqueio de Ramo
/
Eletrocardiografia
Tipo de estudo:
Prevalence_studies
/
Risk_factors_studies
Limite:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
País/Região como assunto:
Asia
Idioma:
En
Revista:
J Am Coll Cardiol
Ano de publicação:
2001
Tipo de documento:
Article
País de afiliação:
Japão