Unravelling novel intracellular pathways in cell-based assays.
Drug Discov Today
; 7(3): 179-86, 2002 Feb 01.
Article
em En
| MEDLINE
| ID: mdl-11815234
ABSTRACT
The pharmaceutical industry is currently facing several challenges to identify and develop novel drug targets. Traditional drug discovery focussed on a small number of well-characterized gene products. Recently, this picture has changed with the completion of the draft sequence of the human genome, which has led to the identification of thousands of novel genes with unknown or poorly understood function. To cope with this overwhelming number of potential drug target candidates, new strategies for the elucidation of gene function, as well as their involvement in intracellular pathways, are required.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Farmacologia
/
Bioensaio
/
Transdução de Sinais
/
Indústria Farmacêutica
Limite:
Humans
Idioma:
En
Revista:
Drug Discov Today
Assunto da revista:
FARMACOLOGIA
/
TERAPIA POR MEDICAMENTOS
Ano de publicação:
2002
Tipo de documento:
Article
País de afiliação:
Alemanha