Chlamydia pneumoniae in infrequently examined blood vessels.
J Clin Pathol
; 55(3): 218-20, 2002 Mar.
Article
em En
| MEDLINE
| ID: mdl-11896076
ABSTRACT
AIM:
To determine the prevalence of Chlamydia pneumoniae DNA in infrequently examined blood vessels.METHODS:
Vessels obtained from 15 men and six women at coronary artery bypass surgery were tested by a nested polymerase chain reaction (PCR) assay for C pneumoniae DNA.RESULTS:
Chlamydia pneumoniae DNA was detected in four of six atheromatous ascending aorta specimens but in none of eight non-atheromatous aorta specimens, in six of 11 atheromatous internal mammary artery specimens but in none of seven non-atheromatous internal mammary artery specimens, in five of seven long saphenous vein specimens showing evidence of disease but in none of 12 specimens without evidence of disease, and in two of three previously grafted veins. Overall, C pneumoniae occurred significantly more often in diseased than in normal vessels (p = < 0.00001).CONCLUSIONS:
Chlamydia pneumoniae is often present in diseased areas of arteries, including the internal mammary arteries, and even in diseased areas of veins. It is not present in apparently healthy areas of either type of vessel.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Arteriosclerose
/
Vasos Sanguíneos
/
Chlamydophila pneumoniae
Tipo de estudo:
Risk_factors_studies
Limite:
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
J Clin Pathol
Ano de publicação:
2002
Tipo de documento:
Article
País de afiliação:
Reino Unido