CD23 negative chronic lymphocytic leukemia of the tonsil: report of a case.
J La State Med Soc
; 154(3): 141-3, 2002.
Article
em En
| MEDLINE
| ID: mdl-12139359
ABSTRACT
We present the case of atypical chronic lymphocytic leukemia presenting as a tonsillar mass in an elderly man. Histological examination of the tumor revealed diffuse submucosal infiltration by small lymphocytes. On flow cytometry, a monoclonal B lymphocytic population expressing CD5, CD19, lambda light chain, but not expressing CD10, CD23, or FMC7 activities, was observed. A diagnostic conundrum occurred with the demonstration on molecular cytogenetic analysis of the chromosomal translocation abnormality, t(11;14)(q13;q32). The diagnosis of CD23 negative chronic lymphocytic leukemia was made after further molecular studies failed to detect the bcl-1 gene rearrangement.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Tonsila Palatina
/
Leucemia Linfocítica Crônica de Células B
/
Receptores de IgE
/
Infiltração Leucêmica
Limite:
Aged
/
Aged80
/
Humans
/
Male
Idioma:
En
Revista:
J La State Med Soc
Ano de publicação:
2002
Tipo de documento:
Article