Drug permeation through membranes V: interaction of diazepam with common excipients.
J Pharm Sci
; 65(2): 207-10, 1976 Feb.
Article
em En
| MEDLINE
| ID: mdl-1255451
The effects of common tablet excipients on the permeation of diazepam through polydimethylsiloxane membranes and on the turnover time of goldfish were studied. The permeability coefficient decreased and the turnover time increased in the presence of talc, polysorbate 80, and, possibly, fumed silicon dioxide, but these parameters were unaffected by lactose, microcrystalline cellulose, and starch.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Cyprinidae
/
Carpa Dourada
/
Diazepam
Limite:
Animals
Idioma:
En
Revista:
J Pharm Sci
Ano de publicação:
1976
Tipo de documento:
Article