Bone homogeneity factor: an advanced tool for the assessment of osteoporotic bone structure in high-resolution magnetic resonance images.
Invest Radiol
; 38(7): 467-72, 2003 Jul.
Article
em En
| MEDLINE
| ID: mdl-12821862
ABSTRACT
RATIONALE AND OBJECTIVES:
Osteoporosis is characterized by low bone mass and inferior structural competence. In this study we introduce the bone homogeneity factor (BHF) as a quantitative measurement of bone structure, which could be equally important as bone mineral density.METHODS:
BHF represents an advanced texture analysis tool based on the spatial autocorrelation function calculated in 9 different directions. These calculations were performed on high-resolution magnetic resonance images of the calcaneus at 3.0 T and compared with dual-energy x-ray absorptiometry measurements of the femoral neck.RESULTS:
The quality and resolution of the high-resolution magnetic resonance images is sufficient for reliably calculating BHF. The mean BHF of the control group (n = 5, mean BHF = 525,0) with normal bone is significantly (P = 0.009, Mann-Whitney U test) higher than in the osteoporotic group (n = 7, mean BHF = 137,8). The BHF correlates with the DXA measurements of the femoral neck (correlation coefficient = 0.75).CONCLUSIONS:
By calculating the BHF, it was possible to distinguish between osteoporotic and nonosteoporotic bone structure. Hence, BHF could be a possible candidate for noninvasive assessment of osteoporotic bone structure giving additional information to routinely used bone mineral densitometry.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Osteoporose
/
Imageamento por Ressonância Magnética
/
Calcâneo
/
Colo do Fêmur
Tipo de estudo:
Observational_studies
Limite:
Aged
/
Female
/
Humans
/
Middle aged
Idioma:
En
Revista:
Invest Radiol
Ano de publicação:
2003
Tipo de documento:
Article
País de afiliação:
Áustria