The clinical effects of hyaluronic acid ester nasal dressing (Merogel) on intranasal wound healing after functional endoscopic sinus surgery.
Otolaryngol Head Neck Surg
; 128(6): 862-9, 2003 Jun.
Article
em En
| MEDLINE
| ID: mdl-12825038
ABSTRACT
OBJECTIVES:
We sought to determine the efficacy of MeroGel, an absorbable hyaluronic acid nasal dressing (HA) in reducing synechia after functional endoscopic sinus surgery (FESS) compared with Merocel, a nonabsorbable packing (NAP) requiring removal.METHODS:
We conducted a blinded, randomized, controlled trial of 37 patients requiring bilateral FESS for chronic sinusitis. Patients were randomized to placement of HA within the right or left middle meatus and NAP on the other side. Patients were evaluated at 2, 4, 6, and 8 weeks postoperatively.RESULTS:
Blinded evaluation revealed 5 patients (14%) with synechia at last follow-up 3 sides (8%) with HA and 3 (8%) with NAP. Thirteen patients (35%) had synechia at any visit, 10 sides (27%) with HA and 9 (24%) with NAP. Seven patients (19%) required lysis of synechia, 5 sides (14%) with HA and 3 (8%) with NAP.CONCLUSION:
We found no statistically significant difference between HA and NAP dressings.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Seios Paranasais
/
Cicatrização
/
Ácido Hialurônico
Tipo de estudo:
Clinical_trials
Limite:
Humans
Idioma:
En
Revista:
Otolaryngol Head Neck Surg
Ano de publicação:
2003
Tipo de documento:
Article
País de afiliação:
Estados Unidos