Antibiotic resistance and serotype distribution of Streptococcus pneumoniae colonizing rural Malawian children.
Pediatr Infect Dis J
; 22(6): 564-7, 2003 Jun.
Article
em En
| MEDLINE
| ID: mdl-12828156
ABSTRACT
Nasopharyngeal swabs were taken from 906 Malawian children <5 years old visiting rural health clinics. Pneumococcal colonization was high, 84% among all children, and occurred early, 65% of it in children <3 months old. Among pneumococcal isolates 46% were nonsusceptible to trimethoprim-sulfamethoxazole, and 21% were nonsusceptible to penicillin. Trimethoprim-sulfamethoxazole use in the previous month was a risk factor for trimethoprim-sulfamethoxazole and penicillin nonsusceptibility. Forty-three percent of isolates were serotypes included in the 7-valent pneumococcal conjugate vaccine, and 37% were vaccine-related serotypes, particularly 6A and 19A.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Penicilinas
/
Streptococcus pneumoniae
/
Combinação Trimetoprima e Sulfametoxazol
/
Resistência a Múltiplos Medicamentos
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Risk_factors_studies
Limite:
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
País/Região como assunto:
Africa
Idioma:
En
Revista:
Pediatr Infect Dis J
Assunto da revista:
DOENCAS TRANSMISSIVEIS
/
PEDIATRIA
Ano de publicação:
2003
Tipo de documento:
Article
País de afiliação:
Estados Unidos