Treatment of Nippostrongylus brasiliensis in normal and SPF rats using tetramisole loaded into zeolite.
J Helminthol
; 66(4): 288-92, 1992 Dec.
Article
em En
| MEDLINE
| ID: mdl-1338071
ABSTRACT
Administration to rats of tetramisole loaded into zeolite was more successful in killing adults of Nippostrongylus brasiliensis than the administration of tetramisole alone. The most successful treatment occurred in SPF (Specific Pathogen Free) rats dosed with tetramisole loaded into zeolite and no worms were present in this group at autopsy eight days post-infection. It is concluded that the slow release of drug from the zeolite matrix improved its efficacy, especially in removing worms from low-grade infections.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Tetramizol
/
Infecções por Strongylida
/
Nippostrongylus
Limite:
Animals
País/Região como assunto:
America do sul
/
Brasil
Idioma:
En
Revista:
J Helminthol
Ano de publicação:
1992
Tipo de documento:
Article
País de afiliação:
Reino Unido