Suppression of alcohol delirium tremens by baclofen administration: a case report.
Clin Neuropharmacol
; 26(5): 258-62, 2003.
Article
em En
| MEDLINE
| ID: mdl-14520166
ABSTRACT
Delirium tremens (DT) is a clinical condition that appears in some patients affected by severe alcohol withdrawal syndrome (AWS). DT represents a serious complication, being characterized by elevated morbidity and mortality. Benzodiazepines are presently the drug of choice; however their use is related to several side effects. Baclofen is a stereoselective gamma-aminobutyric acid (GABAB) receptor agonist. Recent studies show that baclofen is able to suppress alcohol withdrawal symptoms. At present there are no data on the effects of baclofen administration in AWS complicated by DT. Here, we report a case of DT successfully treated with baclofen. This result indicates that the efficacy of baclofen in the treatment of DT should be examined in future clinical trials.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Baclofeno
/
Agonistas GABAérgicos
/
Delirium por Abstinência Alcoólica
Limite:
Adult
/
Humans
/
Male
Idioma:
En
Revista:
Clin Neuropharmacol
Ano de publicação:
2003
Tipo de documento:
Article
País de afiliação:
Itália