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What is tityustoxin?
Arantes, E C; Sampaio, S V; Vieira, C A; Giglio, J R.
Afiliação
  • Arantes EC; Departamento de Física e Química, Faculdade de Ciências Farmacêuticas, Universidade de São Paulo, Brazil.
Toxicon ; 30(7): 786-9, 1992 Jul.
Article em En | MEDLINE | ID: mdl-1509498
Tityus serrulatus scorpion venom was fractionated by gel filtration affording two heterogeneous toxic fractions, T1 and T2; the latter was further fractionated by ion-exchange chromatography. The fraction of T2 eluted with 0.15 M ammonium acetate buffer, originally named 'tityustoxin', was shown to be a pool of several proteins. One of them, TsTX, as well as T1, was also named 'tityustoxin'. The major and perhaps most potent toxin of the venom, gamma-toxin, was eluted with 0.30 M buffer as a highly purified protein and shown to be different from TsTX. gamma-Toxin is contained in both T1 and T2.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Venenos de Escorpião / Neurotoxinas Idioma: En Revista: Toxicon Ano de publicação: 1992 Tipo de documento: Article País de afiliação: Brasil
Buscar no Google
Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Venenos de Escorpião / Neurotoxinas Idioma: En Revista: Toxicon Ano de publicação: 1992 Tipo de documento: Article País de afiliação: Brasil