[Prenatal diagnosis of a probable human chimera after fertilization in vitro]. / Diagnostic prénatal d'une probable chimère humaine après fécondation in vitro.
Gynecol Obstet Fertil
; 32(2): 143-6, 2004 Feb.
Article
em Fr
| MEDLINE
| ID: mdl-15123138
ABSTRACT
Chimerism is the coexistence of more than one cell line in an individual, due to the fusion of originally separate zygotes. It has been very rarely described in humans. A 36-year-old woman referred for in vitro fertilization (IVF) had three embryos transferred leading to a monofetal pregnancy. Ultrasound examination at 17 weeks showed severe intrauterine growth retardation. Amniocentesis revealed a mixture of 46,XY and 46,XX clones. Histopathologic examination showed a dysmorphic fetus with female phenotype and severe growth retardation. Fusion of two of the three embryos (one male and one female) seems to be the most probable mechanism that could explain both cytogenetic and histopathologic observations.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fertilização in vitro
/
Quimera
/
Retardo do Crescimento Fetal
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
Limite:
Adult
/
Female
/
Humans
/
Male
/
Pregnancy
Idioma:
Fr
Revista:
Gynecol Obstet Fertil
Assunto da revista:
GINECOLOGIA
/
OBSTETRICIA
Ano de publicação:
2004
Tipo de documento:
Article
País de afiliação:
França