[Pharmacologic and enzymatic effects of snake venoms from Antioquia and Choco (Colombia)]. / Effectos farmacologicos y enzimaticos de los venenos de serpientes de Antioquia y Choco (Colombia).
Toxicon
; 30(5-6): 611-20, 1992.
Article
em Es
| MEDLINE
| ID: mdl-1519252
ABSTRACT
We compared several pharmacological and enzymatic effects induced by 11 snake venoms from seven species, six of them from different geographic areas of Antioquia and Choco, north-west of Colombia, South America (Bothrops atrox, B. nasutus, B. schlegelii, B. punctatus, Lachesis muta, Micrurus mipartitus), and Crotalus durissus terrificus venom, from specimens captured in other provinces of the country (Tolima, Huila, Meta and Atlantico). Differences were observed in edema-forming, hemorrhage, defibrination, indirect hemolysis, myonecrosis, proteolysis and lethal activity between venoms from different genera or species, as well as according to the geographic area of origin in B. atrox and B. nasutus snake venoms. Bothrops venoms, in particular B. atrox and L. muta, produced major local effects. All of the venoms, including M. mipartitus, had myotoxic effects. The most defibrinating venoms were B. atrox, L. muta, B. punctatus and C. d. terrificus. All of the venoms had indirect hemolytic activity; the venom of M. mipartitus being greatest. The most lethal venoms were those of C. d. terrificus and M. mipartitus. Within Bothrops species, the venom of B. schlegelii was the least active in terms of local and systemic pathologic effects.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Peptídeo Hidrolases
/
Venenos de Serpentes
Limite:
Animals
País/Região como assunto:
America do sul
/
Colombia
Idioma:
Es
Revista:
Toxicon
Ano de publicação:
1992
Tipo de documento:
Article
País de afiliação:
Colômbia