Immunohistochemical and electron-microscopical identification of neuroendocrine cells in the respiratory tract of rats with experimental uraemia.
Folia Morphol (Warsz)
; 63(2): 233-5, 2004 May.
Article
em En
| MEDLINE
| ID: mdl-15232784
ABSTRACT
The aim of the present study was to characterise immunohistochemically and ultrastructurally the neuroendocrine cells in the pulmonary systems of uraemic rats. Pieces of lung and trachea were collected 1, 2 and 4 weeks after nephrectomy. Paraffin-embedded sections were stained with H+E and by silver impregnation. For the identification of neuroendocrine cells immunohistochemical reactions were performed with the use of specific antibodies against calcitonin (CT), somatostatin (SOM), synaptophysin (SYN), neuron-specific enolase (NSE) and calcitonin gene-related peptide (CGRP). For electron microscopy, ultrathin sections were used. The analysis showed an increased number of both the solitary neuroendocrine cells and of neuroepithelial bodies in uraemic rats when compared to control animals.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Células APUD
/
Traqueia
/
Uremia
/
Pulmão
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
Limite:
Animals
Idioma:
En
Revista:
Folia Morphol (Warsz)
Ano de publicação:
2004
Tipo de documento:
Article
País de afiliação:
Polônia