[Influence of single leaf Asarum himalaicum on renal function of rabbits].
Zhong Xi Yi Jie He Xue Bao
; 2(3): 199-202, 2004 May.
Article
em Zh
| MEDLINE
| ID: mdl-15339444
ABSTRACT
OBJECTIVE:
To study the influence of single leaf Asarum himalaicum on the renal function of rabbits.METHODS:
Rabbits were divided into three groups. Asarum himalaicum, Asarum heterotropoides and normal saline were intravenously administered to the rabbits of one group respectively. The urine volume per minute, urine pH, urine glucose, protein and red blood cells, BUN, SCr, TXB2, 6-keto-PGF1alpha, TXB2/6-keto-PGF1alpha, endothelin, p-aminohippuric acid clearance rate and phenolsulfonphthalein excretion rate were tested before and after the administration.RESULTS:
A certain dosage of single leaf Asarum himalaicum caused acute renal failure in rabbits. The indices tested were significantly different between rabbits administered Asarum himalaicum and normal saline. As compared with the rabbits administered Asarum heterotropoides, the results of indices tested decreased, but without statistical significance, except for SCr.CONCLUSION:
The single leaf Asarum himalaicum can cause renal damage to rabbits. Its renal toxicity is lower that that of Asarum heterotropoides.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Folhas de Planta
/
Asarum
/
Preparações de Plantas
/
Rim
Limite:
Animals
Idioma:
Zh
Revista:
Zhong Xi Yi Jie He Xue Bao
Assunto da revista:
MEDICINA
/
TERAPIAS COMPLEMENTARES
Ano de publicação:
2004
Tipo de documento:
Article
País de afiliação:
China