Significance of positive Stenotrophomonas maltophilia culture in acute respiratory tract infection.
Eur Respir J
; 25(5): 911-4, 2005 May.
Article
em En
| MEDLINE
| ID: mdl-15863651
ABSTRACT
Stenotrophomonas maltophilia is a common coloniser of the respiratory tract of patients with chronic lung disease, and, in the absence of pneumonia or bacteraemia, is often ignored by physicians at the Royal Perth Hospital (Perth, Australia). Experience at the Royal Perth Hospital was reviewed to determine whether ignoring S. maltophilia in this setting has any apparent effect on clinical outcome. All patients who presented with an acute respiratory illness and yielded a positive culture for S. maltophilia between 1995 and 2002 were retrospectively reviewed. All subjects had to yield a positive respiratory isolate of S. maltophilia and undergo chest radiography within 24 h of the isolate being obtained. Ninety-two episodes were identified in 89 individuals; 64 showed no evidence of consolidation. Of the study group, 51 (80.0%) received no anti-S. maltophilia antibiotic therapy and 21 (32.8%) had a nosocomially acquired isolate. The overall mortality rate was 20.3%. There was no impact of anti-S. maltophilia therapy on outcome. The only independent predictor of mortality was serum albumin level. As there was no measurable impact of antibiotic therapy, in the absence of consolidation, a positive respiratory tract isolate of Stenotrophomonas maltophilia probably represents colonisation of a severely impaired host rather than invasive disease.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Infecções Respiratórias
/
Infecções por Bactérias Gram-Negativas
/
Stenotrophomonas maltophilia
Tipo de estudo:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
País/Região como assunto:
Oceania
Idioma:
En
Revista:
Eur Respir J
Ano de publicação:
2005
Tipo de documento:
Article
País de afiliação:
Austrália