[Progress in the study of ryanodine receptor-related muscle diseases].
Sheng Li Ke Xue Jin Zhan
; 36(1): 18-22, 2005 Jan.
Article
em Zh
| MEDLINE
| ID: mdl-15881338
ABSTRACT
Ryanodine receptor (RyR), a calcium release channel within the sarcoplasmic reticulum (SR) membrane, is a key protein in skeletal and cardiac excitation-contraction coupling. The structural and functional changes of RyR can result in decoupling of excitation-contraction, and lead to muscle diseases. Current study confirms that RyR is related to the pathogenesis of these diseases. In this review, we look at the current progress in the study on RyR and these diseases to provide the molecular basis in the prevention and therapy of these diseases.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Retículo Sarcoplasmático
/
Músculo Esquelético
/
Canal de Liberação de Cálcio do Receptor de Rianodina
/
Miocárdio
Limite:
Animals
/
Humans
Idioma:
Zh
Revista:
Sheng Li Ke Xue Jin Zhan
Ano de publicação:
2005
Tipo de documento:
Article