Theoretical analysis of single-molecule force spectroscopy experiments: heterogeneity of chemical bonds.
Biophys J
; 90(11): 3851-64, 2006 Jun 01.
Article
em En
| MEDLINE
| ID: mdl-16513778
ABSTRACT
We show that the standard theoretical framework in single-molecule force spectroscopy has to be extended to consistently describe the experimental findings. The basic amendment is to take into account heterogeneity of the chemical bonds via random variations of the force-dependent dissociation rates. This results in a very good agreement between theory and rupture data from several different experiments.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Modelos Moleculares
/
Microscopia de Força Atômica
Tipo de estudo:
Prognostic_studies
Idioma:
En
Revista:
Biophys J
Ano de publicação:
2006
Tipo de documento:
Article
País de afiliação:
Alemanha