[Cowden's disease: a new paediatric observation]. / La maladie de Cowden: une nouvelle observation pédiatrique.
Arch Pediatr
; 13(5): 459-62, 2006 May.
Article
em Fr
| MEDLINE
| ID: mdl-16564682
ABSTRACT
We report on a paediatric observation of Cowden's disease in a 6-year-old child. Familial steroid-resistant nephrotic syndrome was associated to papulous and papillomatous lesions of gingiva and oral mucosa, multiple hamartoma of the back and of upper limbs, facial dysmorphism and follicular thyroid cancer. Thyroid cancer evolved favorably after surgical treatment, radioactive iodine and L-thyroxin supplementation. Nephrotic syndrome evolved to chronic renal insufficiency after 11 years. The early diagnosis of Cowden's disease, or multiple hamartoma syndrome, allows a careful monitoring of the patients who are facing the risk of cancer transformation, which is the principal complication of the condition.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Síndrome do Hamartoma Múltiplo
Tipo de estudo:
Screening_studies
Limite:
Child
/
Humans
/
Male
Idioma:
Fr
Revista:
Arch Pediatr
Ano de publicação:
2006
Tipo de documento:
Article
País de afiliação:
Tunísia