Saponins from Polygala japonica and their effects on a forced swimming test in mice.
J Nat Prod
; 69(4): 591-4, 2006 Apr.
Article
em En
| MEDLINE
| ID: mdl-16643032
ABSTRACT
Five new triterpenoid saponins, polygalasaponins E (1), F (2), G (3), H (4), and J (5), along with eight known ones (6-13), were isolated from the aerial parts of Polygala japonica. Their structures were established by chemical and spectroscopic means. Forced swimming tests on mice showed that saponins 1 and 4 significantly reduce the immobility status by 58.1% and 51.3% at a dosage of 100 mg/kg administrated orally once daily for 5 days, respectively.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Plantas Medicinais
/
Saponinas
/
Triterpenos
/
Medicamentos de Ervas Chinesas
/
Polygala
/
Atividade Motora
Tipo de estudo:
Diagnostic_studies
Limite:
Animals
Idioma:
En
Revista:
J Nat Prod
Ano de publicação:
2006
Tipo de documento:
Article