Does aflatoxin as an environmental mycotoxin adversely affect the renal and hepatic functions of Egyptian lactating mothers and their infants? A preliminary report.
Int Urol Nephrol
; 38(2): 339-42, 2006.
Article
em En
| MEDLINE
| ID: mdl-16868707
ABSTRACT
BACKGROUNDS/AIMS:
Aflatoxin as a mycotoxin constitutes a real human threat. Its presence in human milk was previously reported in different countries. This work is the first Egyptian report that aimed to assess the presence of aflatoxin in both mothers' milk and the infants' sera and studied its correlation with infants' kidney functions.METHODS:
Fifty healthy breast lactating mothers and their infants who were exclusively breast fed for at least 4 months were included. All of them were subjected to thorough laboratory evaluation including determination of aflatoxin concentration by high performance liquid chromatography.RESULTS:
Twenty-four mothers (48%) and their infants had been contaminated with aflatoxin with the following mean contamination levels (ng/ml); mothers' serum of 8.9+/-4.2, mothers' milk of 1.9+/-0.6 and infants' serum of 1.8+/-0.9. The presence of this contamination level is not associated with renal or hepatic dysfunction.CONCLUSION:
Mothers and their infants in our locality showed a relatively high aflatoxin contamination rate. We did not find a correlation of this contamination level and either renal or hepatic dysfunction.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Aleitamento Materno
/
Aflatoxinas
/
Rim
/
Fígado
/
Leite Humano
Tipo de estudo:
Risk_factors_studies
Limite:
Adult
/
Female
/
Humans
/
Infant
/
Newborn
País/Região como assunto:
Africa
Idioma:
En
Revista:
Int Urol Nephrol
Ano de publicação:
2006
Tipo de documento:
Article
País de afiliação:
Egito