Enantiomeric separation of underivatized small amines in conventional and on-chip capillary electrophoresis with contactless conductivity detection.
Electrophoresis
; 27(21): 4375-82, 2006 Nov.
Article
em En
| MEDLINE
| ID: mdl-17024687
ABSTRACT
The determination of the enantiomers of small non-UV-absorbing amines which otherwise can only be achieved with difficulty was possible by using a combination of the chiral crown ether (+)-(18-crown-6)-2,3,11,12-tetracarboxylic acid (18C6H4) and dimethyl-beta-CD as selectors in CE and contactless conductivity measurement for detection. Alkylamines without any other functional group, amino alcohols, species with ether or ester groups and with a cyclic moiety were investigated. The detection limits were found to be about 1.0 microM and the determination is possible up to at least 1.0 mM. The determination of enantiomeric ratios of up to 99.50.5 was also found feasible.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Eletroforese Capilar
/
Eletroforese em Microchip
/
Aminas
Tipo de estudo:
Diagnostic_studies
Idioma:
En
Revista:
Electrophoresis
Ano de publicação:
2006
Tipo de documento:
Article
País de afiliação:
Suíça