AgNOR distribution in serous tumours of the ovary.
Pathologica
; 82(1081): 487-92, 1990.
Article
em En
| MEDLINE
| ID: mdl-1706828
ABSTRACT
The present paper investigated the distribution of AgNOR in serous tumours of the ovary, with a particular attention to borderline lesion and carcinomas. AgNOR are classified as large AgNOR (LN) and small AgNOR (SN) and are counted separately in 100 nuclei for each tumor. Total number of AgNOR was also recorded (TN). The study shows that the mean values of LN, SN and TN increase from adenomas to borderline lesions and carcinomas, with highly significant differences (p less than 0.001). LN show the most impressive differences between borderline lesion and carcinomas, without overlap of values. The follow up of the patients is not long enough for any correlation between AgNOR counts and prognosis, but preliminary data suggest that high AgNOR counts in borderline tumors should be interpreted very cautiously, because they do not seem to have any correlation with a more aggressive behaviour.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Ovarianas
/
Carcinoma
/
Adenoma
/
Região Organizadora do Nucléolo
Limite:
Female
/
Humans
Idioma:
En
Revista:
Pathologica
Ano de publicação:
1990
Tipo de documento:
Article
País de afiliação:
Itália