Late thrombosis of drug-eluting stents after discontinuation of clopidogrel: report of two cases and review of the literature.
Conn Med
; 70(8): 485-90, 2006 Sep.
Article
em En
| MEDLINE
| ID: mdl-17089804
Thrombosis of intracoronary stents is a major complication associated with significant morbidity and mortality. Of concern are case reports of late (more than six months from deployment) drug-eluting stent thrombosis temporally associated with discontinuation of antiplatelet therapy and when stent endothelialization was presumed to be complete. In certain patients it appears that vascular healing at the stented segments is incomplete with increased susceptibility to late thrombosis. We report two cases of late stent thrombosis occuring more than one year after stent deployment and within weeks of discontinuation of clopidogrel. A review of the literature is presented to identify clinical and angiographic predictors of increased risk.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Trombose
/
Trombose Coronária
/
Ticlopidina
/
Inibidores da Agregação Plaquetária
/
Stents
/
Infarto do Miocárdio
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
Limite:
Aged80
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Conn Med
Ano de publicação:
2006
Tipo de documento:
Article
País de afiliação:
Estados Unidos