Lichenoid paraneoplastic pemphigus in the absence of detectable antibodies.
J Am Acad Dermatol
; 56(1): 153-9, 2007 Jan.
Article
em En
| MEDLINE
| ID: mdl-17097371
ABSTRACT
Paraneoplastic pemphigus (PNP) has been described as an antibody-mediated mucocutaneous disease occurring almost exclusively in patients with lymphocytic neoplasms. We describe 4 patients with the clinical features of the lichenoid variant of PNP in the absence of detectable autoantibodies. On the basis of these findings, we conclude that the spectrum of PNP likely includes patients with disease predominantly or exclusively mediated by cytotoxic T cells rather than autoantibodies. The pathophysiology and range of PNP disease are likely more complex than was initially believed.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Síndromes Paraneoplásicas
/
Autoanticorpos
/
Pênfigo
/
Erupções Liquenoides
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
Idioma:
En
Revista:
J Am Acad Dermatol
Ano de publicação:
2007
Tipo de documento:
Article
País de afiliação:
Estados Unidos